关键词: 昼夜温差, 儿童哮喘, 时间序列, 日就诊人数

Abstract:

In order to understand the influence of diurnal temperature range (DTR) on childhood asthma, the 0-14 years old outpatients who had childhood asthma from 2012 to 2015 and the corresponding air temperature data of Shijiazhuang were used to analyze the exposure and response relation between them by applying generalized additive model (GAM) based on time series after controlling the cocktail effect of seasonal variation, holiday effect, air pressure, wind speed and relative humidity. The results show that diurnal temperature range had a “U” relationship with childhood asthma, the total number of childhood asthma increased 1.4% with air temperature increasing 1 ℃ when DTR was more than 8.8 ℃. Children of different ages were affected by DTR difference, the effect of DTR on childhood asthma outpatients who were 0-6 years old presented “U” distribution. However, when DTR increased, the number of 7-14 years old outpatients also increased. When DTR was more than 14.9 ℃, with DTR increase every 1 ℃, the relative risk degree of the number of childhood asthma outpatients was 1.045, and the number of childhood asthma clinics would increase by 4.5%.

Key words:  diurnal temperature range, childhood asthma, time-series, daily outpatients