Net Primary Productivity (NPP) is not only the main parameter for estimating carbon sequestration and oxygen release in ecosystems and measuring terrestrial carbon cycle, but also the main index for evaluating ecosystem health. In view of the limited application of domestic satellites in remote sensing monitoring of grassland NPP, a set of NPP inversion model of grassland NPP in Inner Mongolia was constructed based on FY-3D/MERSI2 data. The NPP of grassland under clear sky condition in Inner Mongolia was obtained by using a strict cloud detection algorithm, which was driven by remote sensing data products and CLDAS meteorological assimilation data, combined with light energy utilization model and ecological process model. In this study, lattice meteorological data with high resolution are introduced, which greatly improves the precision of inversion results. At the same time, based on the observation data and MODIS products, multiple relationship models of above-ground biomass, the Fraction Photosynthetic Active Radiation Absorption Ratio (FPAR) and Normalized Difference Vegetation Index (NDVI) in different months (from May to August) of grassland growth period in Inner Mongolia were constructed, and process parameters such as Leaf Area Index (LAI) and FPAR could be directly estimated based on FY-3D data. By comparing several key ecological process parameters with MODIS products, it is found that they have good correlation and spatial consistency. Finally, the grass observation data of 18 ecological meteorological observation stations in June 2021 were compared with the estimated results, showing that there was a good consistency between them, with a correlation coefficient of 0.86. The NPP inversion using FY-3D/MERSI2 can fully present the general state of vegetation productivity in Inner Mongolia.